(see the links below). And that’s always a qualifier. It was then she sought the guidance of a primary care physician with expertise in nutrition and medical management of obesity, who placed her on a ketogenic diet. any people are also struggling with hypertension, weight gain, fatty liver, dementia, low testosterone, menstrual irregularities and infertility, and more. I’ll pull the trigger myself if I want it. I try to share research, whether it’s my own research from my lab or latest published research, or even old research findings. And what I mean by that is it directs the use of energy like you mentioned a moment ago is energy going to be stored or used or as I had introduced a couple of years ago or wasted and that’s of course ketones. And yet there’s a downside of course to hyperinsulinemia or when insulin is getting too high for too long. And there’s this whole world of are we promoting disordered eating by promoting a low-carb “restrictive diet”. It wants to mobilize fats from fat cells, it wants to mobilize the glucose that’s been stored as glycogen in the liver and it wants to tell the liver to make ketones, so it activates ketogenesis. He has a study called Physiology of Insulin in Man, this big beautiful review paper, it’s so well done just to a quality of writing, etc. So, to give you a sense of my general protocol, I'll cycle in and out of strict ketogenic diet, and then I'll usually have a pretty tight eating window, and I do run a 24, or 36-hour weekly fast. And so it’s a way of keeping the cell regenerating itself in a way, keeping its function optimal, maybe that’s the best way to say it. The ceramide overaccumulate in the cell, creating an insulin resistant state. And I do find I have to be a little more heavy-handed to make up for all the professors who aren’t. You need insulin, here’s your syringe. About five years ago… yeah… by this point… sort of started kind of moving into looking at ketones as independent signaling molecules. Diet Doctor Podcast #56 with Dr. Ethan Weiss 1:02:10 Dr. Ethan Weiss is a preventive cardiologist who supports a low-carb and keto way of eating. And so, even in that sense insulin is good, but protein is too, and I’m sure some people listening to me will be like, Ben, I’m not saying protein’s bad, even though I’m studying it. I’ll wake up around 5:30, maybe five, and work on the book a bit and then the kids will start to wake up at 6:30. Understanding the role of glucagon and insulin with Benjamin Bikman, PhD. I had an ascending aortic aneurysm repaired in 2007 and while eating differently I eat now I was borderline diabetic. So I rage against that idea and I really hope in fact the very students, or anyone who’s claiming that’s an advocate of a low-carb diet– mind you, when I’m in professor mode, I’m not advocating anything, I’m just showing the data. Lower the carbohydrate, I mean it is so rational. Bret:  I imagine– I actually haven’t looked into this, I have to admit, so it’s probably something that not many labs do. So they’re more rigorous, if you will, more resistant to insults. Bret:  Yeah, and that’s really fascinating because for most people, they’re stressing that there has to be a fast, that it’s not just a nutritional method of keeping insulin low. I don’t personally like the low-carb waffles that I make, but my kids do so I make it for them, and that would be something I don’t eat and I don’t bring anything with me. When we drink a ketone, it will enter the cell and mitochondria to be turned into a molecule called acetyl-coA. Evolutionarily, ketogenic diets would be seasonal. I will very rarely eat breakfast. And I love putting eggs in shakes, just rocky style kind of shakes. But there are also forms of insulin resistance with low insulin level. Ketones can as well. So I'll do a blend of fasting, low-carb diet, and then cycling in and out of a strict ketogenic diet. As more research is coming out, the state of nutritional ketosis is fascinating as it opens up unique pathways and prioritization of certain interesting processes in the body. Coincidentally, for us, starchy vegetables are most abundant in the fall. And they know that mom and dad are healthy and fit and some other moms and dads aren’t. Mitochondria go from a fusion state to a fission state. There are instances in human physiology of physiological insulin resistance and that’s the two Ps as I teach it – puberty and pregnancy. 16K likes. Think about an ischemic hypoxic heart; there’s less oxygen and it can maintain ATP production. And then I was seeing, as I started to look through the human clinical data studies that would refer to ketogenic diets. [4:24] Welcome to Dr. Benjamin Bikman on the podcast! And I’ll say, we don’t have that, we just don’t eat that. And sure enough, if the brain can’t use glucose, there’s only one other fuel, that’s the ketone. Dr. Bret Scher: Welcome to the DietDoctor podcast with Dr. Bret Scher. So they become insulin resistant. Plus, Ben shares some of the practical aspects of living low carb in real life — as a father, husband and researcher. [17:42] The risk of the standard American diet. By that time I’d taken a gradual course in endocrinology, so I was familiar with the kind of stereotypical or prototypical glands; the thyroid gland, the gonads, the pituitary, the adrenal glands, these glands that existed in large part to secrete hormones that would have some systemic effect. I’m a member of the American Diabetes Association of course, the rigmarole is, you know, whole grains, low-fat, high starch, pretty high starch and when I thought, I’m not going to rely on any textbook. Cancer, heart disease, Alzheimer’s disease, and diabetes affect millions each year. You drive more insulin. We have more brown fat when we are little. It does get fairly technical at times I have to admit because he does like to talk about the science and the specifics, but importantly we try and bring it back to how the science can apply to us as individuals in our everyday life. I mean even if you are science-minded, which you definitely are and sticking to the science, you still need a louder voice to overcome the hundreds of other voices that are telling the opposite. Ben:  Yeah, but you can understand. The information we provide at DietDoctor.com is not intended to replace consultation with a qualified medical professional. So, that’s pretty fascinating. Ben:  But my frustration with that was– first of all I was glad the student approached me, and as her professor I was very gratified and proud of her for doing that. Glycolysis gene expression, not at all. But nevertheless I then followed that up with my postdoctoral work at Duke Singapore, that was more lipid induced insulin resistance. Professor Bikman earned his Ph.D. in Bioenergetics and a post-doc fellowship at Duke University, Singapore in metabolic disorders. Dr. Benjamin Bikman explains how mitochondria – the power plants of the cells – can use nutrient energy in two different ways. Either a very efficient way, or the mitochondria are being wasteful and using more nutrient energy than needed. Cortisol antagonizes insulin. I do tend to be a very boisterous, somewhat rambunctious speaker, especially when I’m trying to keep my students engaged for two hours… I have a two-hour lecture period. And so when I was thinking about how to structure a conversation about protein I thought, let’s look and see what happens in the insulin to glucagon ratio. In fact, Bret, thanks for bringing it up. 30:24 Benefits of Low Insulin: If insulin is low, your liver is turning fat into ketones. 122. 20:34 The Evolutionary Benefit of Ketones Inducing Wasting: It makes no sense that our bodies would induce this wasting when we are deficient/fasting. And I can look at that and nod my head and give them a thumbs up, but I’m not as much a fasting guy, I’m an insulin guy, and I’m thinking there may be other benefits of the fasting, like just breaking an addiction for food, realizing you don’t have to have that when you think you do. So anyway, finding ultimately the protein, somewhat could eat protein… and if someone was in a state of glucose excess, like getting the protein at the same time as glucose or underlying hyperglycemia, that exaggerated this insulin to glucagon ratio. But on the other hand, and I asked the student this; I said, “Have you had similar conversations “with professors who have been showing data or talking about low fat diets?
How Long Does Revolution Take To Work On Worms, Uma Maheswara Stotram Malayalam Lyrics, What Does A Prince Wear On His Head, Travis Scott Cactus Jack Font, Characteristics Of Ethnic Groups, Pawnbrokers Near Me Open Now, Vista Professional Outdoor Lighting Programming, Mini Cook's Champagne Bottles Bulk, 1949 Chevy Coupe, 1800 Tequila Silver,